Schizophrenia Gwas, Автор: SG Potkin · 2009 · Цитируется: 275 — Show more.

Schizophrenia Gwas, It's true, the score  The number of loci associated with schizophrenia through GWAS has dramatically expanded in the past decade, largely as a function of increasing sample sizes  The most recent schizophrenia GWAS to date identified 270 loci significantly associated with schizophrenia [13] . PURPOSE OF REVIEW: Numerous genome-wide association studies (GWAS) of schizophrenia have been published in the past 6 years, with a number of key reports  Автор: J Duan · 2010 · Цитируется: 75 — The GWAS approach is based on linkage disequilibrium (LD), which is the non-random association of alleles (alternative forms of a polymorphism) at different  Автор: J Hass · 2013 · Цитируется: 33 — Our findings provide new insights into the genetic architecture of a brain structure closely linked to schizophrenia. We curated a high-quality list of 101 genes that  We found suggestive evidence of allelic effects detectable in large GWAS of schizophrenia that might be specific to particular family history subgroups. Автор: J Hass · 2013 · Цитируется: 30 — Patients with schizophrenia and their siblings typically show subtle changes of brain structures, such as a reduction of hippocampal volume. Search for other works by this author on: Oxford Academic · PubMed · Google Scholar. Автор: SG Potkin · 2009 · Цитируется: 275 — Show more. FBIRN. Neurosci. These loci include genes involved in dopamine  Автор: CN Pato · 2000 · Цитируется: 3 — Although evidence exists to support a heritable component to schizophrenia, few details are understood about the genetics of the disorder. 22, 691–699 (2019)  Автор: S Ripke · 2011 · Цитируется: 2198 — The combined stage 1 and 2 analysis yielded genome-wide significant associations with schizophrenia for seven loci, five of which are new (1p21. Schizophrenia Bulletin . Nat. We prioritized two potentially druggable genes in loci that are shared with an addiction GWAS (PDE4B and VRK2). It is unclear whether any of  Genome-wide association study (GWAS): A hypothesis-free approach scanning millions of variants across the genome to identify loci linked to a trait  Автор: SH Shaw · 1998 · Цитируется: 313 — We completed a systematic genome-wide search for evidence of loci linked to schizophrenia using a collection of 70 pedigrees containing multiple affected  Автор: SE Bergen · 2012 · Цитируется: 154 — Numerous genome-wide association studies (GWAS) of schizophrenia have been published in the past 6 years, with a number of key reports published in the last  Автор: AK Tiwari · 2010 · Цитируется: 107 — A consistent observation among the GWAS studies is the association with schizophrenia of genetic markers in the major histocompatibility  Автор: W Cheng · 2021 · Цитируется: 98 — This genetic association study investigates the extent of shared genetic architecture between schizophrenia and brain cortical surface area  Genome-wide association studies (GWAS) of schizophrenia have yielded more than 100 common susceptibility variants, and strongly support a substantial  Автор: K Xu · 2015 · Цитируется: 158 — Next, we investigate whether the schizophrenia GWAS regions are significantly enriched in any group of genes with human-specific expression shifts. Using the  Genome-wide association studies can identify genetic regions that are more likely to be mutated in individuals with a disorder than in controls. However, these  Автор: CA Ross · 2018 — It is agreed in the GWAS literature that: there are at least hundreds and possibly thousands of risk genes for schizophrenia; this set of genes  Автор: J Flint · 2014 · Цитируется: 10 — There is a view that genome-wide association studies (GWAS) have not been particularly helpful when applied to psychiatric diseases. ,. Автор: D Jitoku · 2013 · Цитируется: 4 — Many studies have reported that genetic variants play a major role in the pathogenesis of schizophrenia genome-wide association studies (GWAS) and copy number  Автор: Y Kim · 2018 · Цитируется: 36 — Genome-wide association studies (GWAS) for schizophrenia have identified over 100 loci encoding >500 genes. In silico replication, mRNA expression and  Автор: D He · 2021 · Цитируется: 24 — A Bayesian framework that integrates multi-omics data and gene networks predicts risk genes from schizophrenia GWAS data. gtt, waen5a, 2kyz, khyf, zxpxrh, kq, 0x1ssrcem, aqd, 3jpsb, 46wezr,